Mayo Clinic News Network

News Resources

Items Tagged ‘Florida News Release’

November 14th, 2014 · Leave a Comment

Mayo Clinic Trustees Welcome New Board Member

By Karl W Oestreich

Mary Sue Coleman, Ph.D.

Mary Sue Coleman, Ph.D.

JACKSONVILLE, Fla. — The Mayo Clinic Board of Trustees welcomed Mary Sue Coleman, Ph.D., as a new public member at its quarterly meeting today.

Dr. Coleman is president emeritus of the University of Michigan, (U-M) an institution she led for 12 years before retiring in July 2014. Time magazine named her one of the nation’s “10 best college presidents,” and the American Council on Education honored her with its Lifetime Achievement Award. She previously was president of the University of Iowa.

As University of Michigan president, Dr. Coleman unveiled several major initiatives designed to impact on future generations of students, the intellectual life of the campus, and society at large. The initiatives focused on the interdisciplinary richness of the U-M, student residential life, the economic vitality of the state and nation, global engagement and the value of innovation and creativity. President Obama chose Dr. Coleman to help launch the Advanced Manufacturing Partnership, a national effort bringing together industry, universities and the federal government.

Click here for a bio of Dr. Mary Sue Coleman.

MEDIA CONTACT: Karl Oestreich, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu.

Read the rest of this entry »

View full entry · Comment on this

Tags: Dr Mary Sue Coleman, Florida News Release, Mayo Clinic Board of Trustees, Minnesota news release, News Release


November 10th, 2014 · Leave a Comment

Mayo Clinic Researchers Identify First Steps in Formation of Pancreatic Cancer

By Kevin Punsky

Shown is a region of a pancreas with preneoplastic lesions. Red labeling indicates macrophages, green labeling indicates pancreatic acinar cells that dedifferentiate, and grey labeling indicates further progressed pancreatic lesions.

Shown is a region of a pancreas with preneoplastic lesions. Red labeling indicates macrophages, green labeling indicates pancreatic acinar cells that dedifferentiate, and grey labeling indicates further progressed pancreatic lesions.

JACKSONVILLE, Fla. — Researchers at Mayo Clinic’s campus in Jacksonville say they have identified first steps in the origin of pancreatic cancer and that their findings suggest preventive strategies to explore.

In an online issue of Cancer Discovery, the scientists described the molecular steps necessary for acinar cells in the pancreas — the cells that release digestive enzymes — to become precancerous lesions. Some of these lesions can then morph into cancer.

“Pancreatic cancer develops from these lesions, so if we understand how these lesions come about, we may be able to stop the cancer train altogether,” says the study’s lead investigator, Peter Storz, Ph.D., a cancer biologist.

he need for new treatment and prevention strategies is pressing, Dr. Storz says. Pancreatic cancer is one of the most aggressive human cancers — symptoms do not occur until the cancer is well advanced. One-year survival after diagnosis is only 20 percent. It is the fourth leading cause of cancer death in this country.

The scientists studied pancreatic cells with Kras genetic mutations. Kras produces a protein that regulates cell division, and the gene is often mutated in many cancers. More than 95 percent of pancreatic cancer cases have a Kras mutation.

The researchers detailed the steps that led acinar cells with Kras mutations to transform into duct-like cells with stem cell-like properties. Stem cells, which can divide at will, are also often implicated in cancer.

MEDIA CONTACT: Kevin Punsky, Mayo Clinic Public Affairs, 904-953-0746.
Email: punsky.kevin@mayo.edu Read the rest of this entry »

View full entry · Comment on this

Tags: cancer, Dr Peter Storz, Florida News Release, Mayo Clinic, Medical Research, News Release, Pancreatic Cancer


November 9th, 2014 · Leave a Comment

Combination Therapy Offers Quicker, Less Toxic Eradication of Hepatitis C in Patients with Transplanted Livers

By Paul Scotti

JACKSONVILLE, Fla., Nov. 9, 2014 — All patients with hepatitis C who receive a liver transplant will eventually infect their new livers. These transplanted organs then require anti-viral treatment before they become severely damaged. But traditional post-transplant hepatitis C therapy can take up to a year, is potentially toxic and can lead to organ rejection.

Now, at the American Association for the Study of Liver Diseases (The Liver Meeting® 2014) in Boston, researchers at Mayo Clinic report that use of two new oral medications post-transplant is safe and beneficial, and requires only 12 weeks of treatment.

“This is the first study to examine the use of these two new drugs — simeprevir and sofosbuvir — in liver transplant recipients, and, based on this large study, we find it to be a better option than current treatment,” says the study’s lead researcher, Surakit Pungpapong, M.D., a transplant hepatologist and an associate professor of medicine at Mayo Clinic in Florida.

Journalists: Soundbites with Dr. Pungpapong are available in the downloads.

MEDIA CONTACT: Paul Scotti, Mayo Clinic Public Affairs, 904-953-0199. Email: scotti.paul@mayo.edu Read the rest of this entry »

View full entry · Comment on this

Tags: Florida News Release, Hepatitis C, interferon, Liver Disease, Mayo Clinic in Florida, Mayo Clinic Transplant Center, News Release, ribavirin, simeprevir, sofosbuvir, Surakit Pungpapong


October 23rd, 2014 · Leave a Comment

Mayo Clinic Receives $6 Million for ALS, FTD Research

By Kevin Punsky

Lab image of testingJACKSONVILLE, Fla. — The National Institute of Neurological Disorders and Stroke (NINDS) and the U.S. Department of Defense have awarded researchers at Mayo Clinic’s campus in Jacksonville approximately $6 million in two grants to further their studies aimed at improving the diagnosis and treatment of patients suffering from either amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease and frontotemporal dementia (FTD).

NINDS has awarded Leonard Petrucelli, Ph.D., chair of the Department of Neuroscience, and his colleagues Kevin Boylan, M.D., Rosa Rademakers, Ph.D., and Dennis Dickson, M.D., a five-year P01 grant (P01 NS084974-1) to combine their expertise in neurology, genetics, neuropathology and cell biology. Given that no biomarker or blood test currently exists for clinicians to definitely diagnose ALS or FTD, the funding will allow researchers to improve understanding of C9ORF72-related neurodegeneration, identify potential biomarkers and therapeutic targets, and develop a biological fluid and tissue resource to aid future drug discovery.

MEDIA CONTACT: Kevin Punsky, Mayo Clinic Public Affairs, 904-953-0746.
Email: punsky.kevin@mayo.edu

Read the rest of this entry »

View full entry · Comment on this

Tags: ALS, Dr Dennis Dickson, Dr Kevin Boylan, Dr Leonard Petrucelli, Dr Rosa Rademakers, Florida News Release, FTD, Mayo Clinic, Medical Research, News Release


October 21st, 2014 · Leave a Comment

Trastuzumab (Herceptin) Continues to Show Life-Altering Benefit

By Paul Scotti

large crowd of women in pink t shirts for breast cancer awareness


Years After Treatment for HER2-Positive Early Stage Breast Cancer Trastuzumab Shows Life-Altering Benefit 

JACKSONVILLE, Fla. — After following breast cancer patients for an average of eight-plus years, researchers say that adding trastuzumab (Herceptin) to chemotherapy significantly improved the overall and disease-free survival of women with early stage HER2-positive breast cancer.

They found that the use of trastuzumab produced a 37 percent improvement in survival and a 40 percent reduction in risk of cancer occurrence, compared to patients treated with chemotherapy alone.

These findings, published in the Journal of Clinical Oncology, demonstrate how important trastuzumab has been to the treatment of this form of breast cancer, says the study’s lead author, Edith A. Perez, M.D., deputy director at large, Mayo Clinic Cancer Center and director of the Breast Cancer Translational Genomics Program at Mayo Clinic in Florida. Read the rest of this entry »

View full entry · Comment on this

Tags: Breast Cancer, Dr Edith Perez, Florida News Release, HER2+ breast cancer, Journal of Clinical Oncology, Mayo Clinic Cancer Center, Mayo Clinic in Florida, News Release, trastuzumab Herceptin


September 29th, 2014 · Leave a Comment

Data From Worldwide Trial of Two HER2-Positive Breast Cancer Drugs Shows That Trastuzumab Should Remain as Standard of Care

By Paul Scotti

JACKSONVILLE, Fla., Sept. 29, 2014 — Analysis of more than 8,000 women who participated in the world’s largest study of two treatments for HER2-positive breast cancer reinforces other findings from the clinical trial showing that trastuzumab (Herceptin) should remain the standard of care for this cancer, says a Mayo Clinic researcher.

Read the rest of this entry »

View full entry · Comment on this

Tags: ALTTO, Breast Cancer, Edith Perez, ESMO 2014 Congress, Florida News Release, HER2+ breast cancer, lapatinib, M.D., Mayo Clinic Cancer Center, Mayo Clinic in Florida, News Release, trastuzumab


September 19th, 2014 · Leave a Comment

Mayo Researchers Reveal Pathway that Contributes to Alzheimer’s Disease

By Kevin Punsky

Loss of LRP6 in neurons leads to enhanced buildup of amyloid protein, a pathological hallmark of Alzheimer's disease.

Loss of LRP6 in neurons leads to enhanced buildup of amyloid protein, a pathological hallmark of Alzheimer's disease.

JACKSONVILLE, Fla. — Researchers at Jacksonville’s campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer’s disease patients as well as loss of communication between neurons — both significant contributors to this type of dementia.

Their study, in the online issue of Neuron, offers the potential that targeting this specific defect with drugs “may rejuvenate or rescue this pathway,” says the study’s lead investigator, Guojun Bu, Ph.D., a neuroscientist at Mayo Clinic, Jacksonville, Fla.

“This defect is likely not the sole contributor to development of Alzheimer’s disease, but our findings suggest it is very important, and could be therapeutically targeted to possibly prevent Alzheimer’s or treat early disease,” he says.

Read the rest of this entry »

View full entry · Comment on this

Tags: Alzheimer’s disease, Dr Guojun Bu, Florida News Release, Mayo Clinic, Medical Research, News Release


September 12th, 2014 · Leave a Comment

Physicians Find Liver Transplant Patients Can Avoid Costly Stay In ICU Post Surgery

By Paul Scotti

JACKSONVILLE, Fla., Sept. 12, 2014 — The liver transplant team at Mayo Clinic in Florida has found, based on 12 years of experience, that more than half of patients receiving a new liver can be “fast-tracked” to return to a surgical ward room following their transplant, bypassing a one- or two-day stay in the Intensive Care Unit (ICU).

In the September issue of the American Journal of Transplantation, the physicians and researchers have turned their knowledge of who can be safely fast-tracked into a scoring system that other transplant centers can also use — thus sparing patients potentially overly aggressive treatment and saving substantial health care dollars.

MEDIA CONTACT: Paul Scotti, Mayo Clinic Public Affairs, 904-953-0199. Email: scotti.paul@mayo.edu

Read the rest of this entry »

View full entry · Comment on this

Tags: C Burcin Taner, Florida News Release, liver transplant, M.D., Mayo Clinic in Florida, News Release, Transplant Center


September 12th, 2014 · Leave a Comment

Worldwide Study Demonstrates Accuracy of Genetic Analyses

By Kevin Punsky

E. Aubrey Thompson, Ph.D., Mayo Clinic in Florida

E. Aubrey Thompson, Ph.D., Mayo Clinic in Florida

JACKSONVILLE, Fla. — Physicians envision a future in which genomic data from patients is heavily used to manage care — but experts have questioned the accuracy and reliability of these analyses. Now, a study by 150 researchers in 12 countries finds real strength and agreement across RNA genomic sequencing techniques and laboratories — as well as ways to improve what little variability exists to set a new high standard.

The results of the study were published in Nature Biotechnology in three separate research articles.

These results should provide assurance to patients, clinicians and the research community that genomic sequencing is accurate, says E. Aubrey Thompson, Ph.D., a professor of cancer biology at Mayo Clinic in Florida, one of three institutions that led the study. Dr. Thompson is a study co-author and member of the project leadership. Read the rest of this entry »

View full entry · Comment on this

Tags: cancer biolog, Dr E Aubrey Thompson, Florida News Release, genomic sequencing, Mayo Clinic, Mayo Clinic in Florida, Medical Research, News Release


September 2nd, 2014 · Leave a Comment

Mayo Clinic, University of North Florida Host Tenth Annual Upbeat Pink: A Musical Tribute to Breast Cancer Survivorship

By Paul Scotti

JACKSONVILLE, Fla., Sept. 2, 2014 – Mayo Clinic and the University of North Florida are honoring Upbeat Pink ConcertNational Breast Cancer Awareness Month in October by hosting the tenth annual “Upbeat Pink: A Musical Tribute to Breast Cancer Survivorship” concert on Friday, Oct. 10 at 7:30 p.m. in Lazzara Performance Hall, UNF Fine Arts Building on the university’s campus in Jacksonville. The Upbeat Pink concert is free and open to the public.

The theme for this year’s program, “Dancing with the Survivors,” showcases a variety of dance music performed by the UNF Wind Symphony, conducted by Gordon Brock, D.M.A., and features special guest artist and multi-instrumentalist,  Bill Prince, D.M.A.

Guest speakers will include Laura Vallow, M.D., radiation oncologist at Mayo Clinic and Dianne Wagner, a local breast cancer survivor.
Read the rest of this entry »

View full entry · Comment on this

Tags: Breast Cancer, Breast Clinic, Donna Foundation, Florida News Release, Gordon Brock Bill Prince, Laura Vallow, M.D., Mayo Clinic, News Release, UNF Wind Symphony, University of North Florida, Upbeat Pink, 262 with Donna