- By Susana Shephard
Four-Drug Combo Helps Treat Multiple Myeloma
A four-drug mix of chemotherapy drugs is proving to be highly effective in treatment for patients who are newly diagnosed with the blood cancer multiple myeloma.
The Mayo Clinic-led study shows the multidrug regimen, called CYCLONE (comprised of Cyclophosphamide, Carfilzomib, Thalidomide and Dexamethasone), had strong results in the phase II trial. “Within only four cycles of treatment, 96 percent of patients responded favorably to the therapy,” says lead researcher Joseph Mikhael, M.D., a hematologist at Mayo Clinic in Arizona. “Furthermore, 75 percent experienced a very good partial remission — meaning there was a 90 percent reduction of their tumor. A third of the patients experienced a complete remission, where the tumor was no longer detectable.”
Dr. Mikhael is presenting the study at an American Society of Clinical Oncology conference in Chicago.
Soundbites with Dr. Mikhael are available in the downloads above.
Expert title for broadcast cg:
Dr. Joseph Mikhael, Mayo Clinic Hematologist
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