Mayo Clinic News Network

News Resources

Joe Dangor (@joedangor)

Activity by Joe Dangor

Joe Dangor (@joedangor) posted · Sat, Apr 18 11:26am · View  

Mayo Clinic Researchers Identify Methylated DNA Markers That May One Day Lead To Noninvasive Whole Body Cancer Screening

PHILADELPHIA — A team of Mayo Clinic researchers has succeeded in identifying the source of cancer in patients’ gastrointestinal tracts by analyzing DNA markers from tumors. The results open the possibility that doctors could one day be able to screen for cancer anywhere in the body with a noninvasive blood test or stool sample. Such tests, if they prove practical and feasible, could mean greater convenience for patients and saved lives through earlier diagnosis of cancer, especially rare and often lethal diseases such as pancreatic cancer or lung cancer.

The researchers' findings will be presented on April 21 in a poster presentation at the AACR Annual Meeting 2015 in Philadelphia by John Kisiel, M.D., a gastroenterologist at Mayo Clinic.

MEDIA CONTACT: Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu

Journalists: Sound bites with Dr. Kisiel are available in the downloads.

[...]

Click here to view the rest of the post

Login here to comment.

Joe Dangor (@joedangor) posted · Sat, Apr 18 1:33pm · View  

Metformin Use May Not Improve Survival in Pancreatic Cancer Patients

AACR 2015 Dr. Chaiteerakij

Roongruedee Chaiteerakij, M.D., Ph.D.

PHILADELPHIA -- Use of the diabetes drug Metformin by patients with pancreatic ductal adenocarcinoma may not improve survival according to the results of a study performed at Mayo Clinic and presented today at the AACR Annual Meeting 2015, in Philadelphia by Roongruedee Chaiteerakij, M.D., Ph.D., of Mayo Clinic.

Read
 the press release from the American Association for Cancer Research.

MEDIA CONTACT: Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu

 

Login here to comment.

Joe Dangor (@joedangor) posted · Tue, Apr 7 11:57am · View  

Mayo Clinic Researchers Combine Common Genetic Variants and Other Factors to Improve Breast Cancer Risk Prediction

ROCHESTER, Minn. — Recent large-scale genomic analyses have uncovered dozens of common genetic variants that are associated with breast cancer. Each variant, however, contributes only a tiny amount to a person’s overall risk of developing the disease.

A Mayo Clinic-led team of international researchers has now combined 77 of these common genetic variants into a single risk factor that can be used to improve the identification of women with an elevated risk of breast cancer. This factor, known as a polygenic risk score, was built from the genetic data of more than 67,000 women. The results of the research are published April 9, 2015, in the Journal of the National Cancer Institute (JNCI).

A companion study has extended this finding to show that this measure of genetic variation can be combined with traditional predictors of breast cancer risk such as breast density and family history to improve personalized estimates of breast cancer risk. Those findings appeared in JNCI last month.

MEDIA CONTACT: Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu

Journalists: Sound bites with Dr. Fergus Couch are in the downloads.

[...]

Click here to view the rest of the post

Login here to comment.

Joe Dangor (@joedangor) posted · Tue, Mar 24 12:47pm · View  

Media Expert Alert – Preventive Surgery for Gynecologic Cancers

normal female reproductive organs -illustration of uterus, fallopian tubes, ovaries, cervixMayo Clinic oncologist and gynecologic surgeon Jamie Bakkum-Gamez, M.D., is available to provide context for reporters wishing to better understand preventive surgery for gynecologic cancers.

This is in light of actress Angelina Jolie’s announcement she had her ovaries and fallopian tubes removed as a cancer prevention strategy.

MEDIA: To interview Dr. Bakkum-Gamez, contact Joe Dangor at 507-284-5005 or e-mail newsbureau@mayo.edu

Journalists: Sound bites with Dr. Bakkum-Gamez are available in the downloads.

[...]

Click here to view the rest of the post

Login here to comment.

Joe Dangor (@joedangor) posted · Mon, Mar 23 3:55pm · View  

Could a Tampon Help Predict Endometrial Cancer? Mayo Clinic Researchers Say Yes

ROCHESTER, Minn. — Researchers at Mayo Clinic have shown that it is possible to detect endometrial cancer using tumor DNA picked up by ordinary tampons. The new approach specifically examines DNA samples from vaginal secretions for the presence of chemical “off” switches — known as methylation — that can disable genes that normally keep cancer in check.

The finding is a critical step toward a convenient and effective screening test for endometrial cancer, which is the most common gynecologic malignancy in the United States. The results are published in the journal Gynecologic Oncology.

“Unfortunately, there is no equivalent to a Pap smear or a mammogram for endometrial cancer,” says Jamie Bakkum-Gamez, M.D., a gynecologic oncologist at Mayo Clinic and lead author of the study. “We know that the earlier a woman is diagnosed, the better the likelihood is that she is going to have a positive outcome from cancer treatment. Our goal is to use our findings to develop a tool for the early detection of endometrial cancer that women could use in the comfort of their own homes.”

MEDIA CONTACT:
Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu

Journalists: Several sound bites with Dr. Bakkum-Gamez are available in the download link.

[...]

Click here to view the rest of the post

Login here to comment.

Joe Dangor (@joedangor) posted · Thu, Mar 12 2:51pm · View  

Oncologists Reveal Reasons for High Cost of Cancer Drugs, Recommend Solutions

ROCHESTER, Minn. – Increasingly high prices for cancer drugs are affecting patient care in the U.S. and the American health care system overall, say the authors of a special article published online in the journal Mayo Clinic Proceedings.

“Americans with cancer pay 50 percent to 100 percent more for the same patented drug than patients in other countries,” says S. Vincent Rajkumar, M.D., of Mayo Clinic Cancer Center, who is one of the authors. “As oncologists we have a moral obligation to advocate for affordable cancer drugs for our patients.”

Dr. Rajkumar and his colleague, Hagop Kantarjian, M.D., of MD Anderson Cancer Center, say the average price of cancer drugs for about a year of therapy increased from $5,000 to $10,000 before 2000 to more than $100,000 by 2012. Over nearly the same period the average household income in the U.S. decreased by about 8 percent.

[...]

Click here to view the rest of the post

Login here to comment.

Joe Dangor (@joedangor) posted · Thu, Feb 26 12:46pm · View  

U.S. Women’s Awareness of Breast Density Varies by Race and Ethnicity, Education and Income, Mayo Clinic Study Finds

Disparities in the level of awareness and knowledge of breast density exist among U.S. women, according to the results of a Mayo Clinic study published in the Journal of Clinical Oncology.

Xray of non dense breast with cancer

Image A: Non-dense breast tissue showin.g a small cancer (upper left)

Breast density is the term used to describe the variation in dense tissue on a mammogram image. Fatty breast tissue appears more radiologically translucent than dense (fibroglandular) breast tissue. Regions of a breast that comprise fatty tissue will appear darker on a mammogram, while regions that comprise dense tissue appear whiter.

Dense breast w cancer

Image B: Dense breast tissue with palpable lump, cancer diagnosed (far right center)

Increased breast density has been shown to mask cancers on the mammogram as well as to be associated with future risk of breast cancer. Recent legislation in several states mandates that women be given information about breast density in order to guide decisions about breast cancer screening.

Researchers conducted a national cross-sectional survey of 2,311 women ages 40 to 74 in English and Spanish. The survey response rate was 65 percent. Overall, more than half of women who responded (58 percent) had heard of breast density, 49 percent were aware that breast density affects breast cancer detection and 53 percent knew that breast density is associated with cancer risk.

MEDIA CONTACT:
Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu.

[...]

Click here to view the rest of the post

Login here to comment.

Joe Dangor (@joedangor) posted · Wed, Feb 25 4:16pm · View  

Mayo Clinic’s Measles Virus Therapy for Cancer Profiled in VICE Documentary on HBO

measles virus to fight cancer researches in lab

On Friday, Feb. 27 at 10 p.m. ET/10 p.m. PT, HBO will broadcast a documentary entitled Killing Cancer.

Shane Smith from HBO VICE on measles virus and cancer vaccineVICE founder and host Shane Smith follows pioneering researchers across the U.S. — including specialists from the Mayo Clinic Cancer Center — who are changing the face of modern-day medicine through their work with oncolytic virus therapy.

This revolutionary treatment uses HIV, measles and other viruses that have killed millions to combat cancer. You can view the trailer:

 

 

Login here to comment.

Load More    

Loading information...