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Items tagged as "genome"

Proton Pump Inhibitors Decrease Diversity in Gut Microbiome, Increase Risk for Complications

https://www.youtube.com/watch?v=Y0aPjOFWn9c ROCHESTER, Minn. — Before reaching for that daily antacid, you might consider what it’s doing to the trillions of bugs living in your gut. A new Mayo Clinic study in the open access journal Microbiome shows that people who regularly take proton pump inhibitors (PPIs) have less diversity among [...]

Created by Sam Smith

Reflections on the Genome: Mayo Clinic Radio Health Minute

It's been a little over a decade now since the completion of the human genome project.  In this Mayo Clinic Radio Health Minute, Dr. Gianrico Farrugia reflect on how far we've come and what's ahead. To listen, click the link below. Reflections on the Genome

Created by Joel Streed

Changes in Genetic Testing Recommendations Strengthen Patient Autonomy

ROCHESTER, Minn. ― Recent modifications in recommendations regarding incidental findings (IFs) in genetic testing from the American College of Medical Genetics and Genomics (ACMG) depart from the college’s 2013 recommendations in favor of an individualized approach. Experts in the Bioethics Program of the Mayo Clinic Center for Individualized Medicine published a [...]

Created by Sam Smith

Mapping the Genome

In 2003 researchers mapped out the first human genome. It led to an explosion of knowledge about why people are different from one another. That meant for the first time doctors could learn more about why one person gets cancer or responds to treatment when another doesn't. Researchers at Mayo [...]

Created by Admin

Researchers Identify Role of Cul4 Molecule in Genome Instability and Cancer

Mayo Clinic researchers have shown that a molecule called Cul4 helps to deposit DNA-packaging histone proteins onto DNA, an integral step in cramming yards of genetic code into compact coils that can fit into each cell. When DNA isn’t packaged correctly, it can lead to the genomic instability characteristic of [...]

Created by Dana Sparks

Tumor Genomics: Customizing Treatments for Deadly Prostate Cancer

A new study at Mayo Clinic is using genomic sequencing to develop customized treatments for men with castration-resistant prostate cancer, a progressive and incurable stage of prostate cancer, which no longer responds to hormone therapies that stop or slow testosterone production. Oncologist and principal investigator of the Prostate Cancer Medically Optimized Genome-Enhanced Therapy (PROMOTE) study, Manish Kohli, M.D., says, “Men [...]

Created by Dana Sparks

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