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Items tagged as "PLoS One"

Mayo Clinic Moves Small-Molecule Drugs Through Blood-Brain Barrier

ROCHESTER, Minn. — Researchers at Mayo Clinic have demonstrated in a mouse model that their recently developed synthetic peptide carrier is a potential delivery vehicle for brain cancer chemotherapy drugs and other neurological medications. The findings appear in PLOS ONE. “Not only have we shown that we can transport eight [...]

Created by Bob Nellis

Minnesota Partnership Researchers Uncover Cancer Drug Prospects

MINNEAPOLIS — A team funded by the Minnesota Partnership for Biotechnology and Medical Genomics has uncovered clues to possible drugs for two rare cancers through research involving baker's yeast and a library of chemical compounds. The team from Mayo Clinic and the University of Minnesota published the findings in the [...]

Created by mayonewsreleases

Mayo Clinic Finds Steroids May Shorten Hospital Stay for Pneumonia Patients

ROCHESTER, Minn. — Patients with pneumonia may spend fewer days in the hospital if they are given steroids along with antibiotics and supportive care. That's the finding of a Mayo Clinic analysis of eight randomized-controlled clinical trials involving more than 1,100 patients. The results appear in the March issue of [...]

Created by mayonewsreleases

New Mayo Clinic Approach Could Lead to Blood Test to Diagnose Alzheimer’s

Blood offers promise as a way to detect Alzheimer's disease at its earliest onset. Mayo Clinic researchers say they envision a test that would detect distinct metabolic signatures in blood plasma that are synonymous with the disease — years before patients begin showing cognitive decline. Mayo Clinic pharmacologist and co-author Eugenia Trushina, [...]

Created by Dana Sparks

27 Genes Make Rubella Vaccine Less Effective

Using advanced genetic sequencing technology and analysis, Mayo Clinic vaccine researchers have identified 27 genes that respond in very different ways to the standard rubella vaccine, making the vaccine  less effective for a portion of the population. Mayo Clinic vaccinologist Gregory Poland, M.D., says, “This study highlighted the genes potentially responsible [...]

Created by Dana Sparks