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Items tagged as "Tamoxifen"

Mayo Clinic News Network — Headlines 12/17/14 Mayo Clinic News Network Headlines include: Healthy holiday eating Breast cancer and tamoxifen therapy Sleep tips Journalists: The video is in the downloads. Click here for script.

Created by Dana Sparks

Ability to Metabolize Tamoxifen Affects Breast Cancer Outcomes, Mayo Clinic-Led Study Confirms

ROCHESTER, Minn. — For nearly a decade, breast cancer researchers studying the hormone therapy tamoxifen have been divided as to whether genetic differences in a liver enzyme affect the drug's effectiveness and the likelihood breast cancer will recur. A new study by researchers from the Mayo Clinic Cancer Center and [...]

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Metabolizing Tamoxifen: Mayo Clinic Radio Health Minute

In this Mayo Clinic Radio Health Minute, Dr. Matthew Goetz comments on a study that could impact breast cancer treatment in some women. To listen, click the link below. Metabolizing Tamoxifen

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Endoxifen Shows Promise as Breast Cancer Treatment A Phase I trial of endoxifen, an active metabolite of the cancer drug tamoxifen, indicates that the experimental drug is safe, with early evidence for anti-tumor activity. Mayo Clinic oncologist and lead author of the study Matthew Goetz, M.D., says, “We achieved up to sixtyfold higher levels of endoxifen compared to endoxifen levels [...]

Created by Dana Sparks

Study May Help Cool Hot Flashes

A pill used for nerve pain offers women relief from hot flashes, Mayo Clinic researchers report at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO). They say the agent, pregabalin, decreased hot flash severity and frequency about 20 percent more than did a placebo agent. Thus, [...]

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TUESDAY Q & A: Treatment plan should be based on specific type of breast cancer

DEAR MAYO CLINIC: Why is it that some breast cancers have higher survival rates than others? ANSWER: The main reason for the difference in survival rates is that breast cancer is not just one disease. It is well accepted that there are four distinct molecular categories of breast cancer. However, new data [...]

Created by Dana Sparks

Genetic Variations May Identify Best Candidates for Preventive Breast Cancer Drugs

Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. Mayo Clinic oncologist, James Ingle, M.D., says, “Our findings are important, because we identified genetic factors that could [...]

Created by Dana Sparks

How Breast Cancer Patients Metabolize Tamoxifen Affects Outcomes

A new study confirms that a patient’s ability to metabolize the breast cancer drug tamoxifen affects the outcome of her treatment. Researchers at the Mayo Clinic Cancer Center and the Austrian Breast and Colorectal Cancer Study Group confirm that women with early breast cancer who are treated with tamoxifen and [...]

Created by Dana Sparks

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