ROCHESTER, Minn. — Sept. 3, 2013 — Mayo Clinic researchers have found a way to resynchronize cardiac motion following a heart attack using stem cells. Scientists implanted engineered stem cells, also known as induced pluripotent stem (iPS) cells, into damaged regions of mouse hearts following a heart attack. This regenerative approach successfully targeted the origin of abnormal cardiac motion, preventing heart failure. The findings appear in the September issue of the Journal of Physiology.
MULTIMEDIA ALERT: Video resources, including interviews with Drs. Terzic and Yamada, are available for journalists at theMayo Clinic News Network.
"The discovery introduces — for the first time — stem cell-based 'biological resynchronization' as a novel means to treat cardiac dyssynchrony," says Andre Terzic, M.D., Ph.D., senior author of the study. Dr. Terzic is the Michael S. and Mary Sue Shannon Family Director, Center for Regenerative Medicine, and the Marriott Family Professor of Cardiovascular Diseases Research.