
JACKSONVILLE, Flórida 30 de setembro de 2014 — Análises em mais de 8 mil mulheres, que participaram do maior estudo mundial de dois medicamentos para o câncer de mama HER2-positivo, reforçam outras descobertas de estudos clínicos mostrando que o trastuzumabe (Herceptin) deve permanecer como o padrão de tratamento desse tipo de câncer, diz uma pesquisadora da Clínica Mayo.
JACKSONVILLE, Florida, 30 de septiembre 2014 — Investigaciones en más de 8.000 mujeres, que participaron en el estudio más grande del mundo de dos tratamientos para el cáncer de mama HER2-positivo, refuerzan otros hallazgos de este ensayo clínico que demuestran que el fármaco trastuzumab (Herceptin) debiera seguir siendo el tratamiento estándar en este tipo de cáncer, expresa una investigadora de la Clínica Mayo.
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DEAR MAYO CLINIC: What is the most effective way to treat knee bursitis? I have had it for months and the pain is worsening, but I have heard that even after treatment it can come back. Is there a way to prevent it in the future? ANSWER: Bursitis is a term used to describe a variety of disorders that involve inflammation in the knee’s soft tissues. These problems can be caused by exercise, injury, overuse or infection. In many cases, they resolve on their own with little or no treatment. But some cases of bursitis may require medical care. The right treatment usually depends on the underlying cause of bursitis. Knee bursitis is inflammation of a bursa located near your knee joint. A bursa is a small fluid-filled sac that reduces friction and cushions pressure points between your bones and the tendons and muscles near your joints. Each of your knees has 11 bursae. While any of these can become inflamed, knee bursitis most commonly occurs over the kneecap or on the inner side of your knee below the joint.
Más de 8 de 10 pacientes afirman que volverían a elegir la misma opción, según un estudio de Mayo Clinic ROCHESTER, Minnesota — Cada vez más mujeres con cáncer en un seno eligen la remoción de ambos para reducir el riesgo de cáncer en el futuro. Nuevas investigaciones muestran que, a largo plazo, la mayoría no se arrepiente. Mayo Clinic encuestó a cientos de mujeres con cáncer de mama que se sometieron a mastectomías dobles entre 1960 y 1993, y encontró que casi la totalidad volvería a elegir la misma opción. Estos hallazgos se publican en Annals of Surgical Oncology. El estudio hizo un hallazgo sorprendente: mientras que la mayoría de las mujeres estaba conforme con su decisión, se hayan sometido o no a una reconstrucción mamaria posterior, la probabilidad de decir que volverían a optar por la remoción de ambos senos era mayor en las pacientes que decidieron no hacerse la cirugía reconstructiva. En el grupo que se hizo la cirugía reconstructiva, la probabilidad de haberse arrepentido de sus mastectomías profilácticas era mayor en las mujeres que necesitaron operaciones adicionales, por complicaciones, temas relacionados a los implantes mamarios u otras razones; aunque en general la mayoría en este grupo se sintió conforme con su decisión. “Pienso que este estudio pone literatura científica en manos de quienes al asesorar a las pacientes les dicen, ‘Cualquier decisión que tome, es muy probable que siga conforme con ella en el largo plazo; así que reflexione, y decida lo que considere mejor en su caso’”, dice la autora principal, la Dra. Judy Boughey, cirujana de mama de Mayo Clinic.
THIS WEEK'S TOP STORIES Chronic stress puts your health at risk Your body's stress reaction was meant to protect you. But when it's constantly on alert, your health can pay the price. Caffeine content for coffee, tea, soda and more Are you bothered by headaches, restlessness or anxiety? Your daily caffeine fix may be the culprit. See how much caffeine is in your favorite drinks. Fitness: Tips for staying motivated Many people start fitness programs but stop when they get bored or when results come too slowly. Here are 7 tips to help you stay motivated. EXPERT ANSWERS Alzheimer's: Can a head injury increase my risk? Some research indicates a link between head injuries and Alzheimer's disease. Learn more. Dry mouth treatment: Tips for controlling dry mouth From chewing sugar-free gum to avoiding certain products, find out how to ease dry mouth. Click here to get a free e-subscription to the Housecall newsletter.
DEAR MAYO CLINIC: My family has a history of kidney stones, and I would like to prevent them if possible. What should I do to keep from getting kidney stones? Are there foods or drinks I should avoid? ANSWER: A family history of kidney stones does increase your risk of developing stones. But you can take a number of steps to help prevent kidney stones from forming. One of the most important is to drink plenty of fluids each day. Making certain dietary choices and staying at a healthy weight also can lower your risk. Your kidneys filter waste and excess fluid from your blood. That waste and fluid leave your body through urine. Kidney stones form when urine contains more crystal-forming substances —such as calcium, oxalate and uric acid — than the fluid in your urine can dilute. At the same time, due to your genetics or other factors, your urine may not have substances that keep crystals from sticking together. That creates an ideal environment for kidney stones to form. For people with family members who have had kidney stones, the risk of stones is about twice as high as people that do not have a family history. Other factors that can raise your risk include surgeries that change your digestive process, such as gastric bypass, and diseases that affect your digestion, such as inflammatory bowel disease or chronic diarrhea.
Invenshure ofrece interpretación de la farmacogenómica basada en secuenciación de nueva generación ROCHESTER, Minnesota. — Mayo Clinic e Invenshure anuncian el lanzamiento de Oneome, una compañía para interpretación de la genómica que exporta el amplio conocimiento de Mayo en farmacogenómica por medio de informes concisos y prácticos, para ayudar a los proveedores médicos en todo el mundo a ofrecer los medicamentos adecuados en el momento apropiado. Basados en farmacogenómica, los informes de Oneome se centrarán en ofrecer orientación para fármacos con altos niveles de evidencia en la literatura médica. No se revelaron los términos financieros del acuerdo. El Centro de Mayo Clinic para Medicina Personalizada lidera la colaboración de Mayo con Oneome. “Nuestra propia estructura genética puede tener un impacto significativo en la manera en que nuestros organismos procesan y utilizan los fármacos de prescripción, lo que a su vez afecta el funcionamiento del fármaco anticipado por el médico”, dice el Dr. John Logan Black, facultativo de Mayo Clinic, codirector del Laboratorio de Genómica Personalizada en el Departamento de Medicina de Laboratorio y Patología y cofundador de Oneome. “Hemos desarrollado sofisticados algoritmos de decisión que pueden ayudar a los proveedores médicos a utilizar estudios genómicos para encontrar desde un principio la prescripción adecuada”.
On the next Mayo Clinic Radio, Saturday, September 27 at 9 a.m. CT, we'll discuss coronary artery disease with Chair of the Department of Cardiology at Mayo Clinic Charanjit 'Chet' Rihal, M.D. Why is heart disease such a big problem? How do you tell the difference between heartburn and a heart attack? How do surgeons replace a heart valve without opening your chest? We'll find out this and more. Join us! Myth or Fact: Someone with diabetes is at higher risk of having a heart attack than someone who has already had a heart attack. Follow #MayoClinicRadio and tweet your questions. To listen to the program on Saturday, click here. Mayo Clinic Radio is available on iHeart Radio. Listen to this week’s Medical News Headlines: News Segment September 27, 2014 (right click MP3)
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Rochester, Minn. – Mayo Clinic announced today that it is part of a newly formed consortium, including experts from academic medical centers and commercial genetics laboratories across the country, that has established the Prospective Registry of Multi-Plex Testing (PROMPT), an online registry for individuals and families who have undergone testing for inherited cancer-causing genetic mutations. Co-founded by Mayo Clinic Cancer Center, Memorial Sloan Kettering Cancer Center (MSK), Dana-Farber Cancer Institute and Penn Medicine, the goal of the registry is to provide data vital to improving our understanding of the level of risk associated with and outcomes following testing for “panels” of cancer-associated genes. The consortium is now enrolling patients in the first phase of the study. “An enormous challenge in the practice of medicine today is that posed by panel testing of dozens of cancer genes, some of which are recently discovered and for which we do not have adequate information to guide preventive strategies,” said co-founder, Susan Domchek, M.D., director of the Basser Research Center for BRCA at the University of Pennsylvania’s Abramson Cancer Center. MEDIA CONTACT: Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu
Miss the show? Here's the podcast: Mayo Clinic Radio Full Show 9-27-2014 On the next Mayo Clinic Radio, Saturday, September 27 at 9 a.m. CT, ...
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