Research - January 2012 Archives

MINNEAPOLIS — Researchers from the University of Minnesota in Minneapolis and Mayo Clinic in Rochester, Minn., are another step closer to developing a drug to combat fungal infections — one of the major problems confronting patients with compromised immune systems. The Minnesota Partnership for Biotechnology and Medical Genomics has awarded Mayo biochemist Zhiguo Zhang, Ph.D., and University medicinal chemist Michael Walters, Ph.D., a commercialization grant of $621,934 for the first year of a two-year period. The research team will use the grant for additional studies that will move their drug discovery toward the marketplace. The Need Finding new drugs to fight fungal infections is critical as the numbers of immuno-compromised patients rise due to HIV, organ transplants, and cancer chemotherapy treatments. In certain fungal infections, the mortality rate exceeds 50 percent and in some cases may be as high as 90 percent. Current drugs are becoming compromised as fungi become resistant to them.

ROCHESTER, Minn. — Mayo Clinic nephrologist and researcher Rajiv Kumar, M.D., has been selected to receive the highest professional recognition from the American College of Physicians, the John Phillips Memorial Award, one of the most prestigious honors in internal medicine. Dr. Kumar is internationally recognized for his research accomplishments in nephrology, mineral metabolism and endocrinology, specifically bone disease in the context of kidney failure and the regulation of phosphate and vitamin D metabolism. "Dr. Kumar helped train a generation of nephrologists and served as chair of nephrology with distinction," says Morie Gertz, M.D., chair of internal medicine at Mayo Clinic in Rochester. "His contributions to the understanding of vitamin D and its effects on bone are important enough to impact daily on the lives of patients."