- By April Josselyn
Mayo Clinic PathWays: What’s the diagnosis?
This week's case study highlights a 42-year-old woman with trisomy 21 (the most common form of Down syndrome) and an unrepaired heart defect. She was admitted for vomiting blood and blood in her stool, both thought due to a tear in her esophagus caused by forceful vomiting. Coagulation test results included an elevated prothrombin time (a blood test that measures how long it takes blood to clot). Can you make the diagnosis?