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Kevin Punsky (@kevinpunsky) posted · Fri, Dec 12 10:46am · View  

Mayo Clinic Names Christina Zorn, J.D., as Chief Administrative Officer in Jacksonville, Florida

Christina Zorn, J.D.

Christina Zorn, J.D.

JACKSONVILLE, Fla. — Mayo Clinic has appointed Christina Zorn, J.D., as chief administrative officer of its campus in Jacksonville, Fla., and vice chair of Administration, Mayo Clinic.

She will serve as administrative partner to Gianrico Farrugia, M.D., incoming vice president of Mayo Clinic and chief executive officer of the Jacksonville campus, as previously announced. Zorn assumes her new role on Jan. 1.

“Christina Zorn has significant experience at Mayo Clinic as well as excellent insight into the strengths of Mayo Clinic’s Florida staff and the unique challenges of the local and regional market,” says Dr. Farrugia. “I look forward to working with Christina as we continue the excellent efforts underway in delivering outstanding care to our patients, advancing research and educating the next generation of providers in Florida and throughout the Southeast.”

Zorn has been with Mayo Clinic since 2002. She began her career at Mayo Clinic as a legal counsel and now serves as the chair of the Florida division of the Legal Department. In addition, Zorn has served as an administrator for the Department of Ophthalmology in Florida and for several key initiatives.

She succeeds Robert Brigham, who has served as chief administrative officer in Florida since 2005. Brigham will retire from Mayo Clinic at the end of 2014. Zorn will work closely with Brigham to ensure a smooth leadership transition.

MEDIA CONTACT: Kevin Punsky, Mayo Clinic Public Affairs, 904-953-0746,
punsky.kevin@mayo.edu [...]

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Joe Dangor (@joedangor) posted · Wed, Dec 3 11:18am · View  

Nivolumab shows significant benefit for Hodgkin’s lymphoma in Mayo Clinic co-led phase I study

ROCHESTER, Minn. — A phase I clinical trial of nivolumab found that the immune-boosting drug is a highly effective therapy for Hodgkin’s lymphoma. The multi-institution study, led by Mayo Clinic, indicated that the drug was safe and led to an 87 percent response rate in patients who had failed on other treatments. Results of the study appear in the New England Journal of Medicine.

The findings support further development of nivolumab, which enhances the immune system’s ability to detect and kill cancer cells. The drug has already demonstrated benefit in the treatment of other cancers, particularly melanoma, renal cell cancer, lung cancer and bladder cancer.

“Nivolumab is a very promising agent that is reasonably well-tolerated and can easily be combined with other agents in the future,” says Stephen Ansell, M.D., Ph.D., a hematologist and co-lead author of the study. “There is evidence now that you can fight cancer by optimizing your immune function, either by enhancing signals that stimulate the immune response or blocking signals that dampen it.”

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Bob Nellis (@bobnellis) posted · Thu, Dec 4 11:36am · View  

Mayo Clinic’s Discovery’s Edge Launches Android Platform

DE_CoverROCHESTER, Minn. — Android users no longer have to miss out on all the research discoveries coming from Mayo Clinic. The newest issue of Discovery’s Edge, Mayo Clinic’s research magazine, is now available on all Android devices, as well as the iPad, online and in print. Research news from Mayo Clinic — however, whenever and wherever you want to read it.

Highlights in this issue explore the past, present and future of Mayo Clinic research, including:

Biomarker discovery: Staying one step ahead of cancer

Read about a 12-month snapshot of how four researchers combined their talents to discover biomarkers that could help specific patients with difficult medical issues. In that time span, the Biomarker Discovery Program — part of Mayo Clinic’s Center for Individualized Medicine — found 32 biomarkers using custom algorithms and other innovative approaches that physicians can use to aid patients.

Mayo Clinic plugs into drug discovery

Collaboration is also the story of Mayo Clinic’s latest partnership — with Sanford-Burnham Medical Research Institute. Two organizations looking for just the right counterpart to meet a strategic need found each other at just the right time to fast-track drug discovery for Mayo patients.

Next generation: Developing tomorrow’s biomedical researchers

The path to becoming a biomedical researcher is not for the faint of heart. This issue’s cover story takes a glimpse at three scientists-in-training at Mayo Graduate School and the obstacles they are facing, both personal and professional, as they strive toward careers in research. [...]

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lizatorborg (@lizatorborg) posted · Sat, Nov 22 6:00am · View  

Weekend Wellness: Tracking headaches may help teen see patterns, avoid triggers

DEAR MAYO CLINIC: My daughter, 16, has had headaches off and on for the past year. Ibuprofen seems to help, and she says the headaches are not severe. But I am concerned that they are so frequent. What could be the cause of recurring headaches in teens? young teenaged woman with migraine or tension headache

ANSWER: Headaches in teens are common. In most cases, they are not symptoms of a larger medical problem. But when headaches continue, it is a good idea to have them evaluated. There also are steps to take at home that may help reduce headaches.

There are many kinds of headaches. Two of the most common are tension headaches and migraine headaches. Tension headaches are often described as feeling like a tight band around the head. A migraine headache usually causes intense throbbing on one side of the head. It can be accompanied by nausea, vomiting and sensitivity to light and sound. [...]

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Dana Sparks (@danasparks) posted · Thu, Nov 20 5:00pm · View  

Signs and Symptoms of Pertussis

ZUMBROTA, Minn. — Symptoms of an ordinary common cold are hard not to miss. But could it be worse? Mayo Clinic Health System has diagnosed several confirmed cases of pertussis, also commonly known as whooping cough.

Family medicine physician at Mayo Clinic Health System – Red Wing in Zumbrota, Elizabeth Cozine, M.D. has seen patients present with symptoms. “Children and adults alike can contract whooping cough,” she says. “Yet, a simple vaccination could have prevented many of these cases.” Whooping cough can take one to three weeks for signs and symptoms to appear. They're usually mild at first and resemble those of a common cold:

  • Runny nose
  • Nasal congestion
  • Sneezing
  • Red, watery eyes
  • A mild fever
  • Dry cough

Journalists: Video of baby coughing is available in the downloads.

MEDIA CONTACT: Kristy Jacobson, Mayo Clinic Health System Public Affairs, 507-284-5005, Email:  jacobson.kristy@mayo.edu [...]

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Karl W Oestreich (@KarlWOestreich) posted · Fri, Nov 14 4:08pm · View  

Mayo Clinic Trustees Welcome New Board Member

Mary Sue Coleman, Ph.D.

Mary Sue Coleman, Ph.D.

JACKSONVILLE, Fla. — The Mayo Clinic Board of Trustees welcomed Mary Sue Coleman, Ph.D., as a new public member at its quarterly meeting today.

Dr. Coleman is president emeritus of the University of Michigan, (U-M) an institution she led for 12 years before retiring in July 2014. Time magazine named her one of the nation’s “10 best college presidents,” and the American Council on Education honored her with its Lifetime Achievement Award. She previously was president of the University of Iowa.

As University of Michigan president, Dr. Coleman unveiled several major initiatives designed to impact on future generations of students, the intellectual life of the campus, and society at large. The initiatives focused on the interdisciplinary richness of the U-M, student residential life, the economic vitality of the state and nation, global engagement and the value of innovation and creativity. President Obama chose Dr. Coleman to help launch the Advanced Manufacturing Partnership, a national effort bringing together industry, universities and the federal government.

Click here for a bio of Dr. Mary Sue Coleman.

MEDIA CONTACT: Karl Oestreich, Mayo Clinic Public Affairs, 507-284-5005, newsbureau@mayo.edu.

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Kevin Punsky (@kevinpunsky) posted · Mon, Nov 10 9:00am · View  

Mayo Clinic Researchers Identify First Steps in Formation of Pancreatic Cancer

Shown is a region of a pancreas with preneoplastic lesions. Red labeling indicates macrophages, green labeling indicates pancreatic acinar cells that dedifferentiate, and grey labeling indicates further progressed pancreatic lesions.

Shown is a region of a pancreas with preneoplastic lesions. Red labeling indicates macrophages, green labeling indicates pancreatic acinar cells that dedifferentiate, and grey labeling indicates further progressed pancreatic lesions.

JACKSONVILLE, Fla. — Researchers at Mayo Clinic’s campus in Jacksonville say they have identified first steps in the origin of pancreatic cancer and that their findings suggest preventive strategies to explore.

In an online issue of Cancer Discovery, the scientists described the molecular steps necessary for acinar cells in the pancreas — the cells that release digestive enzymes — to become precancerous lesions. Some of these lesions can then morph into cancer.

“Pancreatic cancer develops from these lesions, so if we understand how these lesions come about, we may be able to stop the cancer train altogether,” says the study’s lead investigator, Peter Storz, Ph.D., a cancer biologist.

he need for new treatment and prevention strategies is pressing, Dr. Storz says. Pancreatic cancer is one of the most aggressive human cancers — symptoms do not occur until the cancer is well advanced. One-year survival after diagnosis is only 20 percent. It is the fourth leading cause of cancer death in this country.

The scientists studied pancreatic cells with Kras genetic mutations. Kras produces a protein that regulates cell division, and the gene is often mutated in many cancers. More than 95 percent of pancreatic cancer cases have a Kras mutation.

The researchers detailed the steps that led acinar cells with Kras mutations to transform into duct-like cells with stem cell-like properties. Stem cells, which can divide at will, are also often implicated in cancer.

MEDIA CONTACT: Kevin Punsky, Mayo Clinic Public Affairs, 904-953-0746.
Email: punsky.kevin@mayo.edu [...]

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lizatorborg (@lizatorborg) posted · Sat, Nov 8 6:00am · View  

Weekend Wellness: Children can get hand-foot-and-mouth disease more than once

DEAR MAYO CLINIC: What are the best ways to treat a toddler who has hand-foot-and-mouth disease? Does she need to be seen by a doctor? Does having it once mean she will not get it again?illustration of little boy with hand foot and mouth disease

ANSWER: Hand-foot-and-mouth disease is caused by a virus. It usually leads to mild illness and discomfort that does not require any specific treatment. You should contact your doctor, however, if your child’s symptoms are persistent or if her symptoms get worse. Although they do build up immunity to it over time, children can get hand-foot-and-mouth disease more than once.

Hand-foot-and-mouth disease is common in young children, most often in kids younger than 5. Children who go to child care centers are at higher risk for the condition than others because hand-foot-and-mouth disease spreads by person-to-person contact.

Hand-food-and-mouth disease is most often caused by a coxsackievirus. A fever is usually the first sign of the illness. Other symptoms appear within a few days. They include a sore throat and blisters or sores on the tongue, gums, back of the throat and inside of the cheeks. Blister-like lesions that are red to gray-white usually appear on the palms of the hands and soles of the feet. In some cases, a red rash also may develop on the thighs, buttocks and groin. Children affected by this disorder may have a general feeling of illness and lose their appetite. [...]

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