• By Richard Dietman

Mayo Clinic Radio: Cardiac Regeneration/Stop-Smoking Drug/Juicing

February 16, 2015

On this week’s Mayo Clinic Radio, fixing a broken heart. Cardiac regeneration uses the body’s own stem cells to repair damage done by heart disease. Mayo Clinic cardiologist Dr. Atta Behfar explains. Also on the program, nicotine dependency expert Dr. Richard Hurt discusses results of a new study about the stop-smoking drug varenicline (Chantix). And Mayo Clinic registered dietitian Katherine Zeratsky explains the risks of juice-only diets.

Myth or Matter-of-Fact: Cardiac regeneration may someday replace the need for surgery to repair heart damage.

To listen to the program at 9 a.m. Saturday, February 21, click here.

Follow #MayoClinicRadio and tweet your questions.

Mayo Clinic Radio is available on iHeartRadio.

Mayo Clinic Radio is a weekly one-hour radio program highlighting health and medical information from Mayo Clinic.

To find and listen to archived shows, click here.


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(A)	Tissue staining comparing SCD1 protein expression in normal thyroid tissue, and anaplastic thyroid carcinoma (ATC). A Hematoxylin counter-stain (light blue) highlights the nuclei of the cells within each tissue section. The punctate dark brown stain within the cells indicates positive SCD1 protein expression. Little positive staining is observed in the normal tissue, however SCD1 is highly expressed in anaplastic thyroid carcinoma tissue suggesting that SCD1 is over-expressed in a tumor-specific manner. 

(B)	Tissue staining comparing Ki67- a nuclear protein that serves as a marker for cell growth, in placebo treated or combination SCD1 inhibitor and Carfilzomib (proteasome inhibitor) treated ATC tumors. A Hematoxylin counter-stain (light blue) highlights the nuclei of the cells within each tissue section. Positive Ki67 stain will color the nuclei brown, and increased Ki67 indicates a faster rate of tumor cell growth. The placebo treated tumors have high levels of Ki67 positive staining compared to the combination treated tumors, indicating that this treatment successfully slows the growth rate of ATC.