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    Mayo Clinic Minute: Keeping those who are medically vulnerable safe from COVID-19

If you or a loved one are immunocompromised, and therefore at a higher risk of becoming severely ill from COIVD-19, it's more important than ever to plan ahead for upcoming holiday gatherings. Among those at heightened risk are cancer and transplant patients who are taking immunosuppression medication, in addition to patients with advanced and untreated HIV/AIDS.

In this Mayo Clinic Minute, Dr. Raymund Razonable, a Mayo Clinic infectious diseases physician who works with transplant patients, will explain the steps patients and their loved ones can take to reduce their risk of getting infected with COVID-19 during the holiday season.

Watch: The Mayo Clinic Minute.

Journalists: Broadcast-quality video (1:29) is in the downloads at the end of this post. Please courtesy: "Mayo Clinic News Network." Read the script.

When it comes to protecting those with weakened immune systems from COVID-19, people can take several steps.

"The No. 1, No. 2, No. 3 (things are) vaccine, vaccine, vaccine. Get vaccinated," says Dr. Razonable. "That's still the best measure to prevent infection."

He recommends that patients who are immunocompromised receive three doses of the Moderna or Pfizer COVID-19 vaccine or two doses of the Johnson & Johnson COVID-19 vaccine.

It's also just as important to keep a circle of safety around you. In other words, ensure family and friends you come into contact with also are vaccinated.

"I usually advise my patients that if you love your relatives who are immunocompromised, then get the vaccine because this will make it less likely for you to get the virus. And if you're around them, that means you are less likely to transmit the virus," says Dr. Razonable.

Keeping track of COVID-19 case counts in their local community can help when deciding risks associated with various activities.

"If the transmission in the community is pretty high, then this is probably not the best time to go out in public areas. If you really have to go out, make sure you know to mask up and try to kind of stay away from large gathering as much as possible," says Dr. Razonable.

Finally, if immunocompromised patients are exposed, they should contact their health care provider right away, even if they don't have symptoms.

Learn more: Expert Alert: 5 ways immunocompromised patients can help protect themselves from COVID-19.


For the safety of its patients, staff and visitors, Mayo Clinic has strict masking policies in place. Anyone shown without a mask was either recorded prior to COVID-19 or recorded in a nonpatient care area where social distancing and other safety protocols were followed.

Information in this post was accurate at the time of its posting. Due to the fluid nature of the COVID-19 pandemic, scientific understanding, along with guidelines and recommendations, may have changed since the original publication date

For more information and all your COVID-19 coverage, go to the Mayo Clinic News Network and mayoclinic.org.

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