- News Releases
Roughly 620,000 new cases of lymphoma were diagnosed worldwide, according to the World Cancer Research Fund International's 2020 report. Survival rates have improved as advances develop in treatment, such as chimeric antigen receptor-T cell therapy (CAR-T cell therapy).
Journalists: Broadcast-quality video (1:02) is available in the downloads at the end of the post. Please courtesy: "Mayo Clinic News Network." Read the script.
CAR-T cell therapy is a personalized treatment giving hope to patients diagnosed with various lymphomas.
"Lymphoma in plain terms is essentially a cancer of your immune system," says Dr. Madiha Iqbal, a Mayo Clinic hematologist and oncologist.
Patients who are newly diagnosed with lymphoma are offered a combination of chemotherapy and antibody-based treatments. But for those who do not respond to two or more lines of such treatments, CAR-T cell therapy may be an option.
"Prior to the advent of CAR-T cell therapy, patients who had failed two lines of chemotherapy had a very poor survival of around six months," says Dr. Iqbal.
Receiving CAR-T cell therapy can take a few weeks as a patient's T cells, which normally help fight off infections, are collected and genetically engineered to target lymphoma.
After low-dose chemotherapy, the modified cells are infused back into the patient. These cells can then attack and destroy the lymphoma.
"Patients who had a very poor prognosis can now potentially be cured of their disease," says Dr. Iqbal.
For the safety of its patients, staff and visitors, Mayo Clinic has strict masking policies in place. Anyone shown without a mask was recorded prior to COVID-19 or recorded in an area not designated for patient care, where social distancing and other safety protocols were followed.
The 2022 SPARK scholars gather for a photo before the Mayo Clinic SPARK Mini Science Fair on Mayo Clinic's campus in Jacksonville, Florida. Back row: ...
In January 2021, after being in remission from melanoma for almost a decade, Christina Armendariz began to feel unwell. The 42-year-old mother went to the emergency ...
Changes to your breast can cause a lot of worry. This is understandable. But not all breast changes are a result of breast cancer. Any breast ...