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The leaders of Mayo Clinic's Vaccine Research Group are emphasizing the need for increased long-term study of vaccines and their mechanisms with future safety of patients in mind.
Gregory Poland, M.D., and Richard Kennedy, Ph.D., write in their commentary in the scientific journal Nature Reviews Immunology that greater focus on understanding vaccines' downstream effects, not only on immunity but also on all the other biological systems will provide information that can help make vaccines safer for all and increase public trust in vaccines.
They call for:
They say no vaccine will be completely free from risks and side effects, but by investing more research dollars in infrastructure, assessment, tracking, analysis and longitudinal studies, the safety of future vaccines ― and patient confidence in them ― can be greatly improved.
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