Mayo Clinic Restores Disrupted Heartbeat with Regenerative Intervention

Mayo Clinic researchers have found a way to resynchronize cardiac motion following a heart attack using stem cells. Senior author of the study Andre Terzic, M.D., Ph.D., says, "The discovery introduces — for the first time — stem cell-based ‘biological resynchronization’ as a novel means to treat cardiac dyssynchrony."

Scientists implanted engineered stem cells, also known as induced pluripotent stem (iPS) cells, into damaged regions of mouse hearts following a heart attack. This regenerative approach successfully targeted the origin of abnormal cardiac motion, preventing heart failure. The findings appear in the September issue of  The Journal of Physiology.

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Journalists: Soundbites with Dr. Terzic are available in the downloads. Sound bites with first author, Satsuki Yamada, M.D.,Ph.D., are also in the downloads including b-roll of her explaining the post-infarction progression slide above.