Collaborating with colleagues at Princess Margaret Cancer Centre in Toronto, researchers from Mayo Clinic in Arizona and the Translational Genomics Research Institute (TGen) in Phoenix have discovered why multiple myeloma frequently recurs after an initially effective treatment that can keep the disease at bay for up to several years.
“Some myeloma cells are too immature to be caught by the drugs and thus hide underground only to reemerge later,” says Keith Stewart, M.B., Ch.B., Dean for Research at Mayo Clinic in Arizona and contributor to the study. “This study has wide implications in the search for a cure of this common blood cancer as this ‘progenitor cell’ will have to be targeted.”
The study is published in the Sept. 9 issue of Cancer Cell.
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