• By Caitlin Doran

Science Saturday: What happens in medical research before clinical trials begin?

July 2, 2022
close-up of a lab worker's hand in a blue glove, handling a DNA specimen

When scientific advances burst into the news, such as a new medication to treat COVID-19 or a new concept like CRISPR for gene editing, people get a glimpse of how a scientific idea becomes a treatment or a tool.

But what's the full story?

Where did that idea come from? What happens in the research lab before clinical trials begin? How is scientific discovery transformed into a potential therapy that is ready to be tested in trials with human participants?

Get these answers and more by watching "The Discovery Science Journey" to learn in three minutes:

  • How the process starts in the lab with discovery science, where researchers ask fundamental questions, such as, "What changes in a cell lead to cancer?"
  • What happens next, as researchers team up to combine their knowledge and speed up the pace of discovery.
  • How researchers navigate the regulations that safeguard the health of clinical trial participants and prepare a discovery to enter clinical trials.

Read the rest of the article on the Discovery's Edge blog.

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Other Mayo Clinic medical research websites: