• By Joe Dangor

Pregabalin may lessen pain from irritable bowel syndrome, Mayo Clinic study finds

October 17, 2016

Multi-racial man with stomach painROCHESTER, Minn. — A pilot study by researchers at Mayo Clinic has found that patients suffering from pain related to irritable bowel syndrome (IBS) may benefit from taking pregabalin, a neuro-pain inhibitor commonly used to treat fibromyalgia. The results of the study were presented today at the annual meeting of the American College of Gastroenterology in Las Vegas.

“There currently are limited treatment options available to fight the abdominal pain associated with IBS,” says Yuri Saito Loftus, M.D., the study's author. “We theorized that pregabalin could potentially be helpful.”

Dr. Saito-Loftus and her colleagues followed 85 patients with IBS who reported high levels of abdominal pain. These patients ranged in age from 18 to 70 years. The placebo-controlled study lasted 12 weeks. Patients who received pregabalin reported significant improvement in pain management, compared to those who received a placebo. Preliminary data also showed improvement in other IBS symptoms, including bloating and diarrhea.

Dr. Saito Loftus cautions that, because the study is small, the results are not definitive. “Our study does provide preliminary evidence that pregabalin may be an additional treatment option for patients with IBS who have failed other treatment options, but more research is needed,” Dr. Saito Loftus says.

###

About Mayo Clinic
Mayo Clinic is a nonprofit organization committed to clinical practice, education and research, providing expert, whole-person care to everyone who needs healing. For more information, visit http://www.mayoclinic.org/about-mayo-clinic or https://newsnetwork.mayoclinic.org/.

MEDIA CONTACT:
Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005, 
newsbureau@mayo.edu

Comment

Please login or register to post a comment.