• By Susan Buckles

Science Saturday: Investigating zombie cells and skin aging

July 16, 2022
La Dra. Wyles usa equipos en su laboratorio para estudio de la piel.

When she was just 8 years old, Saranya Wyles, M.D., Ph.D., would recite the stages of wound healing in Latin terms — rubor, tumor, calor, dolor and functio laesa — to her father at the dinner table. Decades later, that ingrained knowledge would be a cornerstone of her regenerative medicine research, education and practice at Mayo Clinic. Dr. Wyles is a Mayo Clinic dermatologist whose subspecialty is regenerative medicine.

"Dermatology has a natural connection to regenerative medicine because the skin is the largest organ that regenerates in the body. There is so much we can learn about regenerative medicine through the skin," says Dr. Wyles. "The unmet needs of patients also drew me to dermatology. I see a lot of age-associated skin conditions and complex inflammatory skin diseases that need treatment beyond the current available treatment armamentarium. I think the new line of cellular (stem cell-based) and acellular (exosome-based) therapies in regenerative medicine have a lot of potential for skin disorders."

Regenerative medicine is an emerging field that seeks to repair, replace or restore diseased cells, tissue or organs. Mayo Clinic's Center for Regenerative Medicine is leading efforts to integrate new regenerative biotherapeutics into clinical care. It supports Dr. Wyles' research as part of its objective of bringing new cures to the practice.

Read the rest of the article on the Mayo Clinic Center for Regenerative Medicine blog.

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